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Taking an excessive amount of folate or folic acid in complement type may have an effect on psychological function, negatively influence the immune system, and masks a doubtlessly extreme vitamin B12 deficiency . It’s important to note that whereas these vitamins don’t have any observable toxicity, a few of them may interact with medicines and interfere with blood testing results. Therefore, caution ought to be taken with all nutritional supplements. Before combining dietary supplements, people ought to consult a well being care practitioner or the product producer. It can also be important to examine that the day by day quantity taken of every specific nutrient doesn’t exceed Safe Upper Levels.

For extra information about Safe Upper Levels see our Recommended Intake Guidelines. Combining supplements won’t normally interfere with the way they work and in some circumstances could also be helpful, for instance vitamin C helps iron absorption.

It can also increase blood calcium levels, which may lead to organ damage . Vitamin A. While vitamin A toxicity, or hypervitaminosis A, can happen from eating vitamin-A-rich meals, it’s mostly associated with supplements.

  • Eating a traditional, properly-balanced diet won’t lead to toxicity in in any other case wholesome people.
  • However, taking vitamin dietary supplements that comprise megadoses of vitamins A, D, E and K may lead to toxicity.

Symptoms embrace nausea, increased intracranial pressure, coma, and even demise . Note that these are unwanted effects that healthy individuals may experience when taking large doses of those vitamins. Individuals with health situations can expertise much more critical reactions to taking too much of a vitamin.


Supplements do have a role to play for some groups of people. For instance, individuals on long-term restrictive weight reduction diets or folks with malabsorption issues, such as diarrhoea, coeliac disease, cystic fibrosis or pancreatitis, can benefit from dietary supplements. Keep in thoughts that these doubtlessly lethal unwanted side effects are related to taking exceptionally high doses of vitamins. Even so, warning should all the time be taken when consuming any dietary complement. Vitamin D. Toxicity from taking high doses of vitamin D supplements can result in harmful symptoms, including weight loss, appetite loss, and irregular heartbeat.